This report aims to explore the events and trends of the biopharmaceutical industry in 2024 (YTD December 2024). This year, 22 novel antibody drugs have been approved by at least one regulatory agency around the world.
These drugs range from monoclonal antibodies to bispecifics and antibody-drug conjugates (ADCs). ADCs in particular are extremely exciting as cancer therapies, being projected to surpass USD 50 billion by 2030. What’s more, antibody drug approvals are going global, with the United States remaining at the forefront of antibody drug development, but China quickly catching up.
2024 saw several large collaborations and acquisitions of up to $10 billion in value, primarily for ADCs and multispecifics. The majority of M&A deals worth over USD $1B have been in the first half of 2024. Investment in antibody drug startups focuses heavily on the use of artificial intelligence (AI) and bispecifics for inflammatory and immunology diseases.
Biointron’s Q1 2025 annual antibody report aims to explore the events and trends of the biopharmaceutical industry in 2025 (January, February, March).
Resistance to treatment continues to limit the long-term success of many therapies. In oncology, cancers may evade antibody-based treatments through mechanisms such as antigen loss, impaired intracellular trafficking, or suppression of immune responses. To address these challenges, researchers are d
Antibody-drug conjugates (ADCs) couple the specificity of monoclonal antibodies with the cytotoxic potency of chemotherapeutic agents. Recent advances have been reported in both hematologic and solid tumors, with next-generation ADCs overcoming limitations of traditional therapies through improved t
Non–small cell lung cancer(NSCLC) remains the leading cause of cancer-related mortality worldwide. Since 2011, the U.S. Food and Drug Administration has approved over 30 new therapies for advanced NSCLC, primarily tyrosine kinase inhibitors and immune checkpoint inhibitors. Biologic age
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