ハイブリドーマ技術、ディスプレイライブラリ、シグナルB細胞の分選/シークエンシング、および計算モデリングなどの抗体開発技術の進歩により、一度に数千種類のモノクローナル抗体（mAb）をスクリーニングできるようになりました。しかし、「最適な」抗体治療薬を特定するには、高スループット（HTP）発現プラットフォームを使用して迅速な抗体生産と評価が必要です。
Biointronの高スループットのリコンビナント抗体(組み換え抗体)発現プラットフォームは、業界トップクラスの位置にあり、すべての生産を2週間で完了することができます。Biointronは、HEK293またはCHO細胞を使用して、異なるスケールでの迅速な大量の抗体発現を行う柔軟性を提供しています。これにより、大量の生産時間と費用を節約することができます。
Our streamlined HTP production process ensures quality and efficiency at every step, from gene synthesis to purified antibodies.
| ステップ | 詳細 | 作業時間 | 納品 |
|---|---|---|---|
| 遺伝子合成とクローニング |
|
1週間 |
|
| トランジェント発現と精製 |
|
1週間 |
1週間
1週間
Integrating mammalian recombinant protein expression into our workflows, Biointron ensures the production of high-quality antibodies tailored to meet diverse research and therapeutic needs. Our cutting-edge systems streamline production while maintaining precision and scalability, making us the ideal partner for your antibody discovery projects.
Expression System: CHO
SDS-PAGE Purity: > 98%
SEC-HPLC Purity: > 95%
Deliveries:> 1 mg/VHH antibody
Average: 218 mg/L
Biointron’s RushmAb™ small-scale packages are designed to offer cost-effective, time-saving solutions to meet rush needs in as fast as 4 days!
100 ug transfection grade
expression plasmids
Production Timeline: 4
days
1 ml supernatant,
expression plasmids
Production Timeline: 8
days
≥100 ug purified antibody,
expression plasmids
Delivery in 10
days
≥1 mg purified antibody,
expression plasmids
Delivery in 10
days
Biointron delivers antibodies within 2 weeks from sequence to purified product, ensuring rapid project progression.
Clients need to provide the antibody sequence or the hybridoma cell line producing the antibody. If the sequence is unavailable, Biointron offers sequencing services to obtain it.
Biointron utilizes HEK293 and CHO cells, known for efficient recombinant protein production, to express antibodies at varying scales.
Yes, Biointron can produce antibodies in various formats, including IgG, scFv, Fab, and bispecific antibodies, tailored to meet specific research or therapeutic needs.
Biointron employs rigorous quality control protocols, including SDS-PAGE analysis (ensuring purity >95%), low endotoxin levels, and SEC-HPLC detection, to guarantee the highest standards.
Clients receive purified antibody samples, along with detailed reports on production processes, quality control results, and any relevant assay data.
Biointron provides detailed instructions for sample preparation and shipping to ensure the integrity of your materials during transit.
To start, contact Biointron through the website’s inquiry form or email. A consultation will be arranged to discuss project requirements and provide a tailored proposal.
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