Antibodies are an essential part of our immune system, and over the years, scientists have developed a range of antibody-based drugs that are used to treat various diseases. In recent years, many antibody drugs have received approval from the US Food and Drug Administration (FDA) for their safety and effectiveness. Here are the top 10 antibody drugs approved by the FDA:
Humira (adalimumab): This antibody drug is used to treat a range of autoimmune diseases, including rheumatoid arthritis and psoriasis.
Rituxan (rituximab): This antibody drug is used to treat non-Hodgkin's lymphoma, chronic lymphocytic leukemia, and rheumatoid arthritis.
Avastin (bevacizumab): This antibody drug is used to treat certain types of cancer, including colon, lung, and brain cancer.
Herceptin (trastuzumab): This antibody drug is used to treat HER2-positive breast cancer.
Remicade (infliximab): This antibody drug is used to treat autoimmune diseases, including Crohn's disease and rheumatoid arthritis.
Keytruda (pembrolizumab): This antibody drug is used to treat various types of cancer, including melanoma, lung cancer, and head and neck cancer.
Opdivo (nivolumab): This antibody drug is used to treat various types of cancer, including melanoma, lung cancer, and kidney cancer.
Erbitux (cetuximab): This antibody drug is used to treat colon cancer and head and neck cancer.
Prolia (denosumab): This antibody drug is used to treat osteoporosis.
Xolair (omalizumab): This antibody drug is used to treat asthma and allergic rhinitis.
At Biointron, we offer high-quality recombinant antibody production services that can help researchers and biotech companies develop antibody-based drugs for various diseases. Our team of experts can provide customized solutions that meet your specific research needs. Contact us to learn more about our services and how we can help accelerate your research and drug development projects.
Antibody specificity refers to an antibody's ability to selectively bind to a unique epitope on a target antigen while avoiding interactions with unrelated antigens. This property arises from the highly specialized antigen-binding site located in the variable region of the antibody, which determines its unique binding characteristics.
Antibody affinity refers to the strength of the binding interaction between a single antigen epitope and the paratope (binding site) of an antibody. This interaction is a fundamental measure of how well an antibody recognizes its specific antigen target.
Recombinant antibodies are produced using genetic engineering techniques, unlike traditional antibody production, where the immune system generates antibodies without direct control over their sequence. By introducing genes encoding antibody fragments into host cells, such as bacteria or mammalian cells, recombinant antibodies can be expressed, purified, and deployed for applications including research, diagnostics, and therapeutics.
Recombinant antibody expression is a biotechnological process that involves engineering and producing antibodies outside their natural context using recombinant DNA technology.