Image credit: DOI: 10.3390/cancers16040800 In recent decades, the landscape of therapeutic antibodies has undergone a rapid evolution, catalyzing breakthroughs in modern medicine. These antibodies, characterized by their precise targeting and minimal side effects

Antibody combination therapies involve the use of two or more antibodies together as a treatment strategy to enhance the therapeutic effect against diseases, such as cancer or infectious diseases. This approach aims to target different epitopes or antigens simultaneously, increasing the efficacy of the treatment by overcoming resistance mechanisms, reducing the likelihood of disease escape, and providing a broader range of action.

抗体工学は、1975年にKöhlerとMilsteinによってハイブリドーマ技術が発明されて以来、著しい進歩を遂げており、高い特異性を示し副作用を低減した治療薬の開発につながっています。

抗体医薬は、がん、免疫疾患、感染症などの治療において最近の成功例が報告されており、非常に注目され、急速に進化している分野です。